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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11626 | IACS-8968 | IDO/TDO Inhibitor | IDO |
IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO). | |||
T11627 | IACS-8968 R-enantiomer | IDO/TDO Inhibitor (R-enantiomer) | IDO |
IACS-8968 R-enantiomer is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO). | |||
T11628 | IACS-8968 S-enantiomer | IDO/TDO Inhibitor (S-enantiomer) | IDO |
IACS-8968 S-enantiomer is the S-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO). | |||
T4410 | LM10 | Others | |
Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters.... | |||
T11623 | IDO/TDO-IN-1 | Others | |
IDO/TDO-IN-1 is an orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50s: 9.7 and 47 nM). | |||
T74536 | IDO/Tubulin-IN-2 | ||
IDO/Tubulin-IN-2 (HT2) is a powerful inhibitor of both TDO and tubulin. This compound demonstrates significant efficacy against various cancer cell lines, including U87, HepG2, A549, HCT-116, and LO2, with respective IC5... |