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Search Results for " ido/tdo inhibitor "

6

Compounds

Cat No. Product Name Synonyms Targets
T11626 IACS-8968 IDO/TDO Inhibitor IDO
IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO).
T11627 IACS-8968 R-enantiomer IDO/TDO Inhibitor (R-enantiomer) IDO
IACS-8968 R-enantiomer is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO).
T11628 IACS-8968 S-enantiomer IDO/TDO Inhibitor (S-enantiomer) IDO
IACS-8968 S-enantiomer is the S-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO).
T4410 LM10 Others
Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters....
T11623 IDO/TDO-IN-1 Others
IDO/TDO-IN-1 is an orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50s: 9.7 and 47 nM).
T74536 IDO/Tubulin-IN-2
IDO/Tubulin-IN-2 (HT2) is a powerful inhibitor of both TDO and tubulin. This compound demonstrates significant efficacy against various cancer cell lines, including U87, HepG2, A549, HCT-116, and LO2, with respective IC5...
TargetMol